!!This displayer contains script commands. You should enable JavaScripting within your browser preferences, or use another browser!
USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
Search by
Maps
Select Remote Interfaces
[All Interfaces]
SWISS-2DPAGE
World-2DPAGE Portal
World-2DPAGE Repository
Exclude local DBs
has only effect if a remote
interface is selected
Searching in 'USC-OGP 2-DE database' for entry
matching:
K2C7_HUMAN
USC-OGP 2-DE database
:
K2C7_HUMAN
K2C7_HUMAN
General information about the entry
View entry in simple text format
Entry name
K2C7_HUMAN
Primary accession number
P08729
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Keratin, type II cytoskeletal 7; AltName: Full=Cytokeratin-7; Short=CK-7; AltName: Full=Keratin-7; Short=K7; AltName: Full=Sarcolectin; AltName: Full=Type-II keratin Kb7;.
Gene name
Name=KRT7
Synonyms=SCL
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1155
:
pI=5.46; Mw=52976
Cross-references
UniProtKB/Swiss-Prot
P08729; K2C7_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
K2C7_HUMAN
Primary accession number
P08729
Secondary accession number(s)
Q92676 Q9BUD8 Q9Y3R7
Sequence was last modified on
January 11, 2011 (version 5)
Annotations were last modified on
March 15, 2017 (version 186)
Name and origin of the protein
Description
RecName: Full=Keratin, type II cytoskeletal 7; AltName: Full=Cytokeratin-7; Short=CK-7; AltName: Full=Keratin-7; Short=K7; AltName: Full=Sarcolectin; AltName: Full=Type-II keratin Kb7;
Gene name
Name=KRT7
Synonyms=SCL
Encoded on
Name=KRT7; Synonyms=SCL
Keywords
3D-structure
;
Acetylation
;
Coiled coil
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Host-virus interaction
;
Intermediate filament
;
Isopeptide bond
;
Keratin
;
Methylation
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X03212; CAA26956.2
; ALT_SEQ; mRNA
EMBL
X13320; CAA31695.1
; -; Genomic_DNA
EMBL
X13346; CAA31695.1
; JOINED; Genomic_DNA
EMBL
X13347; CAA31695.1
; JOINED; Genomic_DNA
EMBL
X13348; CAA31695.1
; JOINED; Genomic_DNA
EMBL
X13349; CAA31695.1
; JOINED; Genomic_DNA
EMBL
X13350; CAA31695.1
; JOINED; Genomic_DNA
EMBL
X13351; CAA31695.1
; JOINED; Genomic_DNA
EMBL
X13352; CAA31695.1
; JOINED; Genomic_DNA
EMBL
X13353; CAA31695.1
; JOINED; Genomic_DNA
EMBL
AJ238246; CAB41416.1
; -; mRNA
EMBL
AF509887; AAN64031.1
; -; mRNA
EMBL
AF509892; AAN64035.1
; -; Genomic_DNA
EMBL
AF509891; AAN64035.1
; JOINED; Genomic_DNA
EMBL
AC007338; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
AC007494; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
BC002700; AAH02700.1
; -; mRNA
CCDS
CCDS8822.1; -
; .
PIR
B24177; B24177
; .
PIR
S05602; S05602
; .
RefSeq
NP_005547.3; NM_005556.3
; .
UniGene
Hs.411501; -
; .
UniGene
Hs.670221; -
; .
PDB
4XIF; X-ray
; 3.20 A; E/F/G/H=8-16
PDBsum
4XIF; -
; .
ProteinModelPortal
P08729; -
; .
SMR
P08729; -
; .
BioGrid
110053; 11
; .
IntAct
P08729; 7
; .
MINT
MINT-256895; -
; .
STRING
9606.ENSP00000329243; -
; .
DrugBank
DB04959; HspE7
; .
DrugBank
DB01087; Primaquine
; .
iPTMnet
P08729; -
; .
PhosphoSitePlus
P08729; -
; .
SwissPalm
P08729; -
; .
BioMuta
KRT7; -
; .
DMDM
317373583; -
; .
SWISS-2DPAGE
P08729; -
; .
PaxDb
P08729; -
; .
PeptideAtlas
P08729; -
; .
PRIDE
P08729; -
; .
TopDownProteomics
P08729; -
; .
DNASU
3855; -
; .
Ensembl
ENST00000331817; ENSP00000329243
; ENSG00000135480; .
GeneID
3855; -
; .
KEGG
hsa:3855; -
; .
UCSC
uc001saa.2; human
; .
CTD
3855; -
; .
DisGeNET
3855; -
; .
GeneCards
KRT7; -
; .
H-InvDB
HIX0010643; -
; .
H-InvDB
HIX0079487; -
; .
HGNC
HGNC:6445; KRT7
; .
HPA
CAB000028; -
; .
HPA
HPA007272; -
; .
MalaCards
KRT7; -
; .
MIM
148059; gene
; .
neXtProt
NX_P08729; -
; .
OpenTargets
ENSG00000135480; -
; .
PharmGKB
PA30233; -
; .
eggNOG
ENOG410IG4R; Eukaryota
; .
eggNOG
ENOG410YY6B; LUCA
; .
GeneTree
ENSGT00760000118796; -
; .
HOGENOM
HOG000230976; -
; .
HOVERGEN
HBG013015; -
; .
InParanoid
P08729; -
; .
KO
K07605; -
; .
OMA
PGIFEAQ; -
; .
OrthoDB
EOG091G09KR; -
; .
PhylomeDB
P08729; -
; .
TreeFam
TF317854; -
; .
Reactome
R-HSA-6805567; Keratinization
; .
Reactome
R-HSA-6809371; Formation of the cornified envelope
; .
ChiTaRS
KRT7; human
; .
GeneWiki
Keratin_7; -
; .
GenomeRNAi
3855; -
; .
PRO
PR:P08729; -
; .
Proteomes
UP000005640; Chromosome 12
; .
Bgee
ENSG00000135480; -
; .
CleanEx
HS_KRT7; -
; .
Genevisible
P08729; HS
; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; TAS:Reactome; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005882; C:intermediate filament
; NAS:UniProtKB; .
GO
GO:0045095; C:keratin filament
; IEA:InterPro; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0005198; F:structural molecule activity
; IEA:InterPro; .
GO
GO:0070268; P:cornification
; TAS:Reactome; .
GO
GO:0031424; P:keratinization
; TAS:Reactome; .
GO
GO:0016032; P:viral process
; IEA:UniProtKB-KW; .
InterPro
IPR001664; IF
; .
InterPro
IPR018039; Intermediate_filament_CS
; .
InterPro
IPR032444; Keratin_2_head
; .
InterPro
IPR003054; Keratin_II
; .
InterPro
IPR009053; Prefoldin
; .
PANTHER
PTHR23239; PTHR23239
; 1; .
Pfam
PF00038; Filament
; 1; .
Pfam
PF16208; Keratin_2_head
; 1; .
PRINTS
PR01276; TYPE2KERATIN
; .
SMART
SM01391; Filament
; 1; .
SUPFAM
SSF46579; SSF46579
; 1; .
PROSITE
PS00226; IF
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
[
Home
]